Context: Chronic diseases (CD) and common mental disorders (CMD) are responsible for the majority of deaths and morbidity worldwide. Both CD and CMD are increasingly present in primary care and supporting patients with CD and CMD represents a complex task for nurses, and little is known about self-management support (SMS) by nurse in this specific context. Objective: The aim of this review was to synthesize the existing knowledge on nurse-led SMS of patients with CD and CMD in primary care. The secondary objectives were to describe the direct and indirect components of SMS and factors that may influence the delivery of SMS. Design: Using Arksey and O’Malley’s method, a scoping review was undertaken to map the existing literature. CINAHL, MEDLINE, PsychINFO, Scopus, and Emcare were searched. No time limit was applied. The concepts searched were self-management support, primary care and nurse. Setting: The studies to be included had to: include nurse-led SMS intervention in primary care; target adult (18yo and more) with at least 1 CD and 1 CMD simultaneously; and be written in French or English. Studies were excluded if: the patients only had CD or CMD; targeted specific problems (obstetrical, gynecological, severe mental disorders, palliative care, oncological, AIDS); or the nurse-led SMS took place in hospitals or at home. From 3438 eligible articles, 33 were included in this review. The screening process was made by 2 authors. Intervention/Instrument (as pertinent): A mixed thematic analysis, based on Miles, Huberman and Saldana, was conducted for this review. The PRISMS taxonomy, by Pearce and Taylor, was used as a deductive framework to map the direct (n=14) and indirect (n=5) components of SMS. An inductive approach was used to describe the main factors that may influence SMS. Analysis was made by the presenting author and another author. Anticipated Results: While still in progress, results will focus on the main components of nurse-led SMS in primary care, including a clear description of the interventions (e.g., different psychological strategies of support, approaches/mode of delivery/frequency, type of plans, nurses’ training and more), and on main factors that may influence SMS on many level (e.g., patient, provider, intervention-level). Conclusions: This overview of nurse-led SMS of patients with CD and CMD maps the components and factors that may influence SMS. With these results, recommendations for further research delivery will be made.