The NAPCRG Pearls are the top research studies presented at the NAPCRG Annual Meeting each year that will impact clinical practice.

2021 Annual Meeting Pearls

2021 NAPCRG Pearls Coming Soon!

2020 Annual Meeting Pearls

Socioeconomic Impact of COVID19 and Willingness to be Vaccinated in African American/Black & Hispanic/Latinx Asthmatic Adults
Brian Manning MPH; Frank Rockhold PhD, MSc, FASA, FSCT; Joel Shields MA; Wilson Pace MD, FAAFP; Jennifer Carroll MD, MPH; Juan Carlos Cardet MD, MPH; Lilin She PhD; Jacqueline Rodriguez-Louis MPH, M.Ed.; Victoria Forth PA-C, MA, MMS; Elliot Israel MD; Paulina Arias Hernandez MSW; Nancy Maher MPH; Maureen Fagan DNP, FNP-BC, FAAN

Impact of COVID-19 on Colorectal, Breast and Cervical Cancer Screening Rates in Primary Care Practices: a PBRN Initiative
Laura Schad MPH; Christopher Morley PhD, MA; Laura Brady PhD, PF; Laurene Tumiel-Berhalter PhD; Alexandrea Bentham BS; Karen Vitale MSEd; Gary Noronha MD; Carlos Swanger MD; Amanda Norton MSW 

Are ACE inhibitors and Angiotensin Receptor Blockers associated with all-cause mortality in patients with COVID-19 infection?
William Hinton

Regular Eating of Breakfast and Overall and Cardiovascular Mortality
Dana King MD, MS; Jun Xiang

Does an active geriatric evaluation prevent functional decline in primary care? A pragmatic cluster randomized trial
Yolanda Mueller MD; Nicolas Senn MD, PhD; Stefanie Monod

Needs and Coping Behaviors of U.S. Youth during the COVID-19 Pandemic
Marika Waselewski MPH; Eric Waselewski MD; Tammy Chang MD, MPH, MS

Experiencing Racism: Women's Stories of Powerlessness and Invisibility in Healthcare
Anmol Hans BS; Catherine Kothari PhD; Yvonne Jackson EdD, PT, DPT; Joi Presberry MPH; Elissa Allen PhD, RN; Elishae Johnson PhD; Evelyn McWilliams BS; Lynette Gumbleton BA; amy nelson MS, RN

Delayed antibiotic prescribing by general practitioners in the UK: a choice experiment
Liz Morrell PhD

The impact of long-term opiate therapy tapering on co-morbid chronic conditions
Elizabeth Magnan MD, PhD; Anthony Jerant MD; Alicia Agnoli MD, MPH, MHS; Daniel Tancredi PhD; Joshua Fenton MD, MPH

Risk of overdose and mental health crisis among patients prescribed long-term opioids undergoing dose tapering
Alicia Agnoli MD, MPH, MHS; Anthony Jerant MD; Elizabeth Magnan MD, PhD; Daniel Tancredi PhD; Joshua Fenton MD, MPH

Rethinking the frequency of cardiovascular risk assessment for patients not on medications
Lenard Lesser MD, MSHS; James McCormack PharmD

What are family physicians curious about? A qualitative analysis of 45 research questions posed for the FMD RapSDI program
Cory Lutgen, BS, BSc; Angie Lanigan, MPA, RD; Elisabeth Callen, PhD; Jennifer Carroll, MD, MPH

Single disease guidelines do not address clinical needs of the multimorbid patient
L. Olivia Tseng, MD, PhD; Shanjot Brar; Victoria Su, BPharm, MBA, PharmD; Hetesh Ranchod, MD, FRCPC; Martin Dawes, MD, PhD, MBBS, FRCGP; Diane Lacaille, MD, FRCPC, MHSc; Craig Mitton

2019 Annual Meeting Pearls

Effects of oseltamivir in primary care patients with influenza-like illness: a randomised open trial in 15 European countries
Theo Verheij, MD, PhD

A novel clinical algorithm to predict low-density lipoprotein cholesterol (LDL-C) response for statin management
Stephen Weng, PhD

Active Surveillance Uptake in a Population-based Survey of Men with Low-risk Prostate Cancer
Jinping Xu, MD, MS

Alcoholic versus Aqueous Chlorhexidine for skin antisepsis- the AVALANCHE trial
Clare Heal, PhD

Aspirin for primary prevention: comparison of studies before and after the era of statins and colorectal cancer screening
Mark Ebell, MD, MS; Frank Moriarty, PhD, BPharm

Coronary Artery Calcium Scoring as a Feasible Risk Stratification Strategy in a Primary Care Practice
Ed Bujold, MD, Chief Physician Strategist for KPN Health; Elisabeth Callen, PhD; Natalia Loskutova, MD, PhD

Diagnostic accuracy of a smartphone-operated 1-lead ECG for detecting rhythm and conduction abnormalities in primary care
Jelle Himmelreich, MD, MSc

Home Blood Pressure monitoring to differentiate appropriate inaction from therapeutic inertia in clinically uncertain cases
Sonal Patil, MD, MSPH; Nuha Wareg, MBBS, MPH; Mark Kaiser; Jamie Smith, MA; Michael LeFevre, MD, MSPH, M.D., M.S.P.H.

MIRtazapine added to SSRIs or SNRIs for Treatment Resistant Depression in Primary Care: a placebo controlled randomised trial
David Kessler, MRCPsych, MRCGP

Overscreening for cancer among older adults in the US: The role of usual source of care
Jennifer Moss, PhD; Alan Adelman, MD, MS; William Curry, MD, MS; Siddhartha Roy, DrPH, MPH; Eugene Lengerich, MS, VMD; Joie Cooper, BA, MS; Mack Ruffin, MD, MPH

PCR point of care test for group A streptococci in patients with an uncomplicated acute sore throat
Ronny Gunnarsson, MD, PhD; Bradley Elliott, MBBS, FRACGP, B.Biomed.Sc; Hilary Gorges; Clare Heal, PhD

Should we de-prescribe blood pressure lowering drugs in the elderly? Results from the OPTiMISE medication reduction trial
James Sheppard, PhD; Jonathan Mant, MD; Richard Hobbs, FMedSci; Richard McManus, PhD, MBBS, FRCGP, FRCP; Paul Little, MD, MBBS, MCRP, MRCP; Sue Jowett, PhD, BSc, MSc; Rupert Payne, PhD, MRCGP, FRCPE; Jenni Burt

2018 Annual Meeting Pearls

Opportunistic Screening for Heart Failure With Natriuretic Peptides in Patients With Atrial Fibrillation: A Meta-Analysis of Individual Participant Data of Four Screening Studies
Sander van Doorn, MD, PhD; Geert-Jan Geersing; Rogier Kievit; Yvonne van Mourik; Loes C. Bertens; Evelien E.S. van Riet; Leandra Boonman - de Winter; Karel G.M. Moons; Arno W. Hoes; Frans Rutten, MD, PhD

Measuring What Matters In and From Primary Care
Rebecca Etz, PhD; Kurt Stange, MD, PhD; Stephen Zyzanski, PhD; Martha Gonzalez; Jonathan O'Neal; Sarah Reves, FNP, MBA; Robert Phillips Jr, MD, MSPH

The Social Media CAGE: A Rapid Assessment of Problematic Social Media Use Among Youth
Kristin Pacl, MD; Yue Guo; Tammy Chang, MD, MPH, MS  

Uptake of Active Surveillance for Low-Risk Prostate Cancer in a Population-Based Cohort
Jinping Xu, MD; Cathryn Bock, PhD; Elaine Brockman; Michael Goodman; James Janisse; Jacquelyn Keen; Loree Mincey; Kendra Schwartz, MD, MSPH 

Patient Experiences With Pain As State Prescription Opioid Policies Change: Qualitative Study
Morhaf Al Achkar, MD, MSCR, FAAFP

Pediatric HITSS: A Short Screening Tool to Detect Childhood Physical and Sexual Abuse in Clinical Settings
Amer Shakil, MBA, MD; Philip Day, PhD; Sarah Woods, PhD; Jessica Chu; Samantha Bridges

Colorectal Cancer Prevention and All-Cause Mortality Reduction: A Meta-Analysis of the U.S. Preventive Services Task Force Evidence Report
Andrew Swartz

Intra-Articular Hypertonic Dextrose Prolotherapy Reduces Knee Pain in Knee Osteoarthritis: A One Year Blinded Randomized Controlled Trial
David Rabago, MD; Ricky Wu; Kenneth Reeves, MD; Dicken Chan; Benjamin HK Yip; Vincent Chung; Samuel, Yeungshan Wong; Regina Sit 

Prolotherapy, Physiotherapy and Combination Care for Lateral Epicondylalgia: A 3-Arm Single-Blinded Randomized Clinical Trial
Michael Yelland; David Rabago, MD; Michael Ryan; Shu-Kay Ng; Dinusha Vithanachchi; Nagarajan Manickaraj; Leanne Bisset

United States Pharmacopeia Patient-Centered Prescription Bottle Label Standards and Medication Adherence
Paul Smith, MD; Kenneth Schellhase, MD, MPH; Henry Young; David Mott; Farah Pathan; Steve Sparks, MS

2017 Annual Meeting Pearls

Cough Drops: Cause for Concern?
Danika Johnson; Robert Mead; David Hahn, MD, MS; Korey Kennelty, MSc, PharmD, PhD

Can We Increase the Rate of Obtaining Advance Directives in Our Primary Care Clinics?
Marie Sandoval, MD; Allen Repp, MD, MSc

Aromatase Inhibitors are Associated with a Higher Fracture Risk than Tamoxifen A systematic Review and Meta-Analysis
Ling-I Olivia Tseng; John Spinelli; Carolyn Gotay; Wan Yu Ho; Mary McBride, MS; Martin Dawes, MD PhD FRCGP

Oral Steroids for the Resolution of Otitis Media with Effusion in Children
Nick Francis, PhD, MD, BA; Chris Butler; Rebecca Cannings-John; Debbie Harris; Kerenza Hood; Colin Powell; Amanda Roberts; Victoria Shepherd; Emma Thomas-Jones; Cherry-Ann Waldron

Chronic Opioid Toxicity: A Clinically Important Concept, Narrative, Literature Review
Irina Kudrina, MD; Yoram Shir; Gillian Bartlett, PhD; Leon Tourian

Screening for Hypothyroidism in pregnancy
Andrei Aldea; Nebras Alghazawi; Roland Grad, MD, MSc, CCFP, FCFP; Mark Karanofsky

Using project ECHO to advance Health Care Delivery in Underserved Communities
Leslie Carlin, PhD; Allison Crawford; Ruth Dubin; Agi Erickson; Mandy Lamb; John Thomas IV

To Test or Not to Test: The Role of Glucose Self-Monitoring in Primary Care Patients With Non-Insulin Treated Type 2 Diabetes
John Buse, MD, PhD; Mark Weaver, PhD; Maihan Vu, MPH, DrPH; Madeline Mitchell, MURP; Tamara Blakeney, BS; Kimberlea Grimm, BAS; Jennifer Rees, RN, CPF; Franklin Niblock, BS; Katrina Donahue, MD, MPH

What Do Patients Taking Antidepressants Worry About? Analysis of a Consumer Medicines Call Centre
Mieke van Driel, MD, MSc, PhD; Samantha Hollingworth; Treasure McGuire, BSC, PhD, BPharm, GDCHP, GCHEd

Primary Care Physicians' Perspectives About the Use of Antipsychotics and Other Medications for Symptoms of Dementia
John William Kerns, MD; Jonathan Winter, MD; Rebecca Etz, PhD; Katherine Winter; Anton Kuzel, MD, MHPE

2016 Annual Meeting Pearls

Did Introduction of Medical Homes With Mandatory After-Hours Provision Reduce Emergency Department Utilization
Tara Kiran, MD; Rahim Moineddin, PhD; Alex Kopp; Eliot Frymire, MA, BEd; Richard H. Glazier, MD, MPH

Stakeholder Agreement Regarding Primary Care “Measures that Matter”
Rebecca S. Etz, PhD; Marshall Brooks, PhD; Martha Gonzalez, BA; Melissa S Hayes, BS; Anton J. Kuzel, MD, MHPE; Heather Librandi, BSC, EMT-P; Kurt C. Stange, MD, PhD

"Give Me a Reasonable Alternative"; Antipsychotics, Dementia, and Virginia Primary Care Physicians
Anton J. Kuzel, MD, MHPE; Jonathan Winter, MD; Rebecca S. Etz, PhD; Katherine Winter; Christine Carlson Kerns, RN; John William Kerns, MD

Prevalence of Atypical Pathogens in Patients With Sore Throat: A Meta-Analysis
Christian Marchello, MS; Mark H. Ebell, MD, MS

Why Do Female GPs Earn Less Than Their Male Colleagues?
Christopher Harrison, Bpsych, MSocH; Clare Bayram; Helena C. Britt, PhD; Janice Charles

Does Prompt Receipt of a Discharge Note by a Patients’ Family Physician Reduce the Rate of Readmissions and Emergency Room Visits in a Universally Funded Health Care System?
Liisa Jaakkimainen, MD, MSc, CCFP; Hong Lu; Jacqueline Young, MSc; Karen Tu, MD, MSc, CCFP, FCFP

Medicare Advantage Enrollees Have Fewer Avoidable Hospitalizations and More Appropriate Hospitalizations Than Traditional Medicare Enrollees: Results From a 12 State Study
Yalda Jabbarpour, MD; Stephen Petterson, PhD; Peter M Wingrove; Andrew Bazemore, MD, MPH

Patient Factors Associated With Successful Weight Loss in Obese Sedentary Primary Care Patients
Charles Buckley Eaton, MD, MS; Kim Gans; Sheri Hartman, PhD; Bess Marcus; Patricia Risica; Mary Roberts

Measuring Continuity in Primary Care and its Impact on Costs and Hospitalizations
Andrew Bazemore, MD, MPH; Stephen Petterson, PhD

Primary Care Physician Advice to Pursue Watchful Waiting is Associated With Less Low-Value Testing
Joshua J. Fenton, MD, MPH; Larissa May; Anthony F. Jerant, MD; Peter Franks, MB, BS


2015 Annual Meeting Pearls

Physical Exercise for Late Life Depression: Tailored Treatments Between Psychiatry and Primary Care
Klea Bertakis, MD, MPH; Mario Amore; Fabrizio Asioli; Luigi Bagnoli; Marco Menchetti; Martino Murri; Micro Neri; Francesca Neviani; Matteo Siena; Guilio Toni; Ferdinando Tripi; Stamatula Zanetidou; Donato Zocchi

Sterile Versus Non-Sterile Gloves for Minor Surgery in General Practice
Clare Heal and Shampavi Sri Haran

The Fit Family Challenge: A Primary Care-Based Pediatric Obesity Program
Bonnie Jortberg, PhD, RD, CDE; Raquel Rosen; Sarah Roth

Prescription Opioid Dose and Duration and Risk for Depression in Three Large Healthcare Center Patient Populations
Jeffrey Scherrer, PhD; Joanne Salas, MPH; Laurel Copeland; Brian Ahmedani; Eileen Stock; Thomas Burroughs, PhD, MA, MS; F. David Schneider, MD, MSPH; Kathleen Bucholz; Mark Sullivan; Patrick Lustman

Adjunctive Screening for Breast Cancer in Women with Dense Breasts: A Systematic Review
Joy Melnikow, MD, MPH; Joshua Fenton, MD, MPH; Evelyn Whitlock, MD, MPH; Diana Miglioretti, PhD; Jamie Thompson, MPH; Meghan Weyrich, MPH

Does Iron Deficiency Without Anemia in Infancy Affect Long Term Developmental Outcomes? Prospective 6 Year Cohort Study
Dee Mangin; Claire Dowson; David Fergusson; Elisabeth Wells

The Effectiveness of Maintenance SSRI Treatment in Primary Care Depression to Prevent Recurrence: Multicentre Double Blinded Placebo Controlled RCT. 
Dee Mangin; Claire Dowson; Roger Mulder; Elisabeth Wells; Les Toop; Tony Dowell; Bruce Arroll, MBChB, PhD

Not as Transient as the Name Suggests: Fatigue, Psychological and Cognitive Impairment Following Transient Ischemic Attack (TIA)
Grace Moran; Melanie Calvert; Max Feltham; Tom Marshall; Ronan Ryan

Missed Opportunities for Prevention of Stroke and Transient Ischaemic Attack (TIA) in Primary Care
Grace Moran; Melanie Calvert; Max Feltham; om Marshall; Ronan Ryan

Oral Steroids for Acute Cough (OSAC): A UK Multi-Centre, Placebo Controlled, Randomised Trial
Alastair Hay 


2014 Annual Meeting Pearls

The Reduction in ED and Hospital Admissions From Medical Home Practices is Specific to Primary-Care-Sensitive Chronic Conditions
Green LA, Markovitz A, Chang HC, Paustian M

Clinical Effectiveness of Collaborative Care Management For Depression Over Time
Garrison, GM; Angstman, KB; O’Connor S; Williams MD; Lineberry TW

Use of Antidepressants in Patients with Depression and Cardiometabolic Disease
Bhautesh Jani, David Purves, Sarah Barry, Colin McCowan, Jonathan Cavanagh, Frances Mair

Continuity of Care: Does Having the Same Primary Care Provider Over Time Matter?
S.T. Wong, A. Katz, Peterson, S., & Taylor, C. 

A Prognostic Algorithm to Predict Hospitalization Among Children Presenting to Primary Care with Acute Cough and RTI: The ‘TARGET’ Prospective Cohort Study
Alastair D Hay, Niamh M Redmond, Andrew M Lovering, Barry Vipond, Brendan Delaney, Hannah Christensen, Hannah V Thornton, John P Leeming, Margaret Fletcher, Matthew Thompson, Paul Little, Peter Muir, Sophie Turnbull, Beth Stewart, Tim J Peters and Peter S Blair on behalf of the TARGET study team

Comparison of Osteoporosis Risk Assessment Tools in Women 50-64 Years Old
Jennifer L. Pecina MD, Lindy Romanovsky, MD Stephen P. Merry MD, Kurt A. Kennel MD, Tom D. Thacher MD

Does an Increase in Opioid Dose lead to an Increase in Depression?
Scherrer JF, Salas J, Lustman PJ, Burge S, Schneider FD, for the Residency Research Network of Texas Investigators. Pain. 2015;156:348-355

Gaps in Knowledge: What do Primary Care Patients Know about the Opioid Medication they Have Been Prescribed?
LS Wallace, L McDougle, WF Miser, RK Wexler

Autoinflation as a Treatment of Otitis Media with Effusion in Primary Care: A Randomized 
Controlled Trial

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Kelly S, Yao G, Raftery J, Mant D, Little P

Are Antibiotics the Only Treatment Option for Urinary Tract Infection? – A Comparative Effectiveness Trial 
Gágyor & J Bleidorn, K Wegscheider, G Schmiemann, M Kochen, E Hummers-Pradier


2013 Annual Meeting Pearls

Shared Decision-Making in Palliative Care: Clinical Implications for the Practice of Family Medicine
Bélanger E, Rodríguez C, Groleau D, Légaré F, & Marchand R.

Has this patient with chest pain coronary artery disease? Diagnostic utility of a clinical decision rule.
J Haasenritter, S Bösner, N Donner-Banzhoff (Philipps University Marburg, Germany)

How often do patients with musculoskeletal (MSK) complaints newly treated with NSAIDs, subsequently consult their GP because of an adverse drug reaction (ADR)
AR Koffeman, AR van Buul, VE Valkhoff, GW ‘t Jong, PJE Bindels, J van   der Lei, MCJM Sturkenboom, PAJ Luijsterburg, SMA Bierma-Zeinstra

A Comparison of the Male Osteoporosis Risk Estimation Score (MORES) and the FRAX® in Identifying Men at Risk for Osteoporosis
Alvah R. Cass, MD, SM, Angela J. Shepherd, MD, Rechelle Asirot, MD, Maimoona Nizami, MD & Manju Mahajan, MD

The True Blue model of collaborative care using practice nurses as case managers for depression alongside diabetes or heart disease: a randomised trial. 
Morgan MAJ, Coates MJ, Dunbar JA, et al. 

Systematic review of the diagnostic accuracy of capillary refill time for serious illness in children
S Fleming, P Gill, C Jones, A Van den Bruel, J Taylor, C Heneghan, M Thompson

Current and future use of point-of-care test in primary care: an international survey in Australia, Belgium, the Netherlands, the United Kingdom, and the United States 
Jeremy Howick, et al.

PCMH Implementation and Primary Care Provider and Staff  Burnout: A Process Analysis
Diana Carvajal MD, MPH, Elizabeth Alt MD, MPH, Claudia Lechuga MS, Stephanie Neves BS, MA, Arthur Blank PhD, M. Diane McKee MD, MS

Does Cardiovascular Risk Predict Statin Use?
Michael Johansen MD, MS, Ohio State University, Lee Green MD MPH, Ananda Sen PhD, Sheetal Kircher MD, MS, Caroline Richardson MD MS.  

PCMH Transformation
Rachel Hope, MD, The Christ Hospital/University of Cincinnati Family Medicine Residency ; Miranda Moore, PhD, & Andrew Bazemore, MD, The Robert Graham Center

Performance of a Rapid Influenza Detection Test (RIDT) in Ambulatory Primary Care Wisconsin: 2009-2013
Temte JL, Barlow S, Greene P, Haupt T, Reisdorf E, Wedig M, Shult P, Giorgi A, Fowlkes A.  University of  Wisconsin

Depression and Opioid Use Increase Risk of Incident Myocardial Infarction
Scherrer JF, Schneider FD, Hauptman PJ, Freedland KE and Lustman PJ, Saint Louis and Washington Universities School of Medicine 

Helping Patients Reach a Balanced Understanding of Controversial Cancer Screening Recommendations:The Impossible Dream?
B Saver, R Luckmann, M Hayes, K Mazor, G Bacigalupe, J Calista, N Esparza, T Gorodetsky

Does the management of patients with chronic non-malignant pain (CMNP) differ between those with and without co-existing mental illness?
Elder NC, White C, Regan S – University of Cincinnati Department of Family and Community Medicine

Using Lean Management to Improve Opioid Prescribing for Pain in Ambulatory Care
Connie van Eeghen DrPH, Amanda Kennedy PharmD, Mark Pasanen MD,  Benjamin Littenberg MD, Charles MacLean MD,
University of Vermont

The potential role of NT-proBNP in screening for heart failure and in predicting prognosis
Richard Hobbs, Care Taylor, Andrea Roalfe, Rachel Iles, University of Oxford

Is montelukast an effective treatment for postinfectious cough?
Wang K, Birring SS, Taylor K, Fry NK, Hay AD, Moore, M, Jin J,Perera R, Farmer A, Little P, Harrison TG, Mant D, Harnden A.





Social Media


11400 Tomahawk Creek Parkway
Leawood, KS 66211